Cargando…

Identifying brain networks in synaptic density PET ((11)C-UCB-J) with independent component analysis

BACKGROUND: The human brain is inherently organized into distinct networks, as reported widely by resting-state functional magnetic resonance imaging (rs-fMRI), which are based on blood-oxygen-level-dependent (BOLD) signal fluctuations. (11)C-UCB-J PET maps synaptic density via synaptic vesicle prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Xiaotian T., Toyonaga, Takuya, Hillmer, Ansel T., Matuskey, David, Holmes, Sophie E., Radhakrishnan, Rajiv, Mecca, Adam P., van Dyck, Christopher H., D’Souza, Deepak Cyril, Esterlis, Irina, Worhunsky, Patrick D., Carson, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452380/ https://www.ncbi.nlm.nih.gov/pubmed/34000404 http://dx.doi.org/10.1016/j.neuroimage.2021.118167

Ejemplares similares

Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and (11)C-UCB-J PET study
por: Fang, Xiaotian T., et al.
Publicado: (2023)

Partial volume correction analysis for (11)C-UCB-J PET studies of Alzheimer’s disease
por: Lu, Yihuan, et al.
Publicado: (2021)

Principal component analysis of synaptic density measured with [(11)C]UCB-J PET in early Alzheimer’s disease
por: O'Dell, Ryan S., et al.
Publicado: (2023)

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11)C]UCB‐J
por: Mecca, Adam P., et al.
Publicado: (2022)

Feasibility of imaging synaptic density in the human spinal cord using [(11)C]UCB-J PET
por: Rossano, Samantha, et al.
Publicado: (2022)

Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand (11)C-UCB-J
por: Bini, Jason, et al.
Publicado: (2020)

Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [(11)C]UCB-J
por: O’Dell, Ryan S., et al.
Publicado: (2021)

(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies
por: Nicastro, Nicolas, et al.
Publicado: (2020)

Synaptic Loss in Frontotemporal Dementia Revealed by [ (11)C]UCB‐J Positron Emission Tomography
por: Malpetti, Maura, et al.
Publicado: (2022)

Automated radiosynthesis of [(11)C]UCB‐J for imaging synaptic density by positron emission tomography
por: Milicevic Sephton, Selena, et al.
Publicado: (2020)

Human biodistribution and dosimetry of [(11)C]-UCB-J, a PET radiotracer for imaging synaptic density
por: Cawthorne, Christopher, et al.
Publicado: (2021)

Synaptic density in carriers of C9orf72 mutations: a [(11)C]UCB‐J PET study
por: Malpetti, Maura, et al.
Publicado: (2021)

Molecular pathology and synaptic loss in primary tauopathies: an (18)F-AV-1451 and (11)C-UCB-J PET study
por: Holland, Negin, et al.
Publicado: (2021)

Lower synaptic density is associated with depression severity and network alterations
por: Holmes, Sophie E., et al.
Publicado: (2019)

Potential of [(11)C]UCB-J as a PET tracer for islets of Langerhans
por: Puuvuori, Emmi, et al.
Publicado: (2021)

Validation and test–retest repeatability performance of parametric methods for [(11)C]UCB-J PET
por: Tuncel, Hayel, et al.
Publicado: (2022)

Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging
por: Matuskey, David, et al.
Publicado: (2020)

Improved synthesis of SV2A targeting radiotracer [(11)C]UCB-J
por: Rokka, Johanna, et al.
Publicado: (2019)

Validation and noninvasive kinetic modeling of [(11)C]UCB-J PET imaging in mice
por: Bertoglio, Daniele, et al.
Publicado: (2019)

PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging
por: Toyonaga, Takuya, et al.
Publicado: (2022)

UCB HCT in FLT3+ AML
por: Ustun, Celalettin, et al.
Publicado: (2017)

Kinetics and 28-day test–retest repeatability and reproducibility of [(11)C]UCB-J PET brain imaging
por: Tuncel, Hayel, et al.
Publicado: (2020)

Imaging the effect of ketamine on synaptic density (SV2A) in the living brain
por: Holmes, Sophie E, et al.
Publicado: (2022)

2181 Age-related change in 5-HT6 receptor availability in healthy male volunteers measured with 11C-GSK215083 PET
por: Radhakrishnan, Rajiv, et al.
Publicado: (2018)

In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET
por: Mecca, Adam P., et al.
Publicado: (2020)

Gone to Pot – A Review of the Association between Cannabis and Psychosis
por: Radhakrishnan, Rajiv, et al.
Publicado: (2014)

Measuring brain synaptic vesicle protein 2A with positron emission tomography and [(18)F]UCB-H
por: Bahri, Mohamed Ali, et al.
Publicado: (2017)

PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies
por: Bhatt, Shivani, et al.
Publicado: (2020)

Nicotine Use and Metabotropic Glutamate Receptor 5 in Individuals With Major Depressive and Posttraumatic Stress Disorders
por: Baldassarri, Stephen R., et al.
Publicado: (2023)

Sapap3 deletion causes dynamic synaptic density abnormalities: a longitudinal [(11)C]UCB-J PET study in a model of obsessive–compulsive disorder-like behaviour
por: Glorie, Dorien, et al.
Publicado: (2020)

Drug characteristics derived from kinetic modeling: combined (11)C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A
por: Naganawa, Mika, et al.
Publicado: (2022)

Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [(18)F]UCB-H PET imaging
por: Vogler, Letizia, et al.
Publicado: (2023)

Isoextraction Studies of Partition of UCB Between Chloroform and Aqueous Solution
por: Hahm, Joon Soo, et al.
Publicado: (1987)

Reducing the osteoporosis treatment gap: an interview with UCB's Pascale Richetta
por: Richetta, Pascale
Publicado: (2017)

Cerebellar and Prefrontal Cortical Alterations in PTSD: Structural and Functional Evidence
por: Holmes, Sophie E., et al.
Publicado: (2018)

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder
por: Scheinost, Dustin, et al.
Publicado: (2018)

The pharmacokinetics of [(18)F]UCB-H revisited in the healthy non-human primate brain
por: Goutal, Sébastien, et al.
Publicado: (2021)

Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density
por: Yang, Yanghong, et al.
Publicado: (2023)

Microglial depletion and activation: A [(11)C]PBR28 PET study in nonhuman primates
por: Hillmer, Ansel T., et al.
Publicado: (2017)

Preclinical radiation dosimetry for the novel SV2A radiotracer [(18)F]UCB-H
por: Bretin, Florian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8j718lv59u41t8i19pcd5bed72