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Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures

While studies on embryonic stem cells have been actively conducted, little is known about the epigenetic mechanisms in human embryonic stem cells (hESCs) in extended culture systems. Here, we investigated whether CpG island (CGI) methylation patterns of 24 tumor suppressor genes could be maintained...

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Detalles Bibliográficos
Autores principales:	Kang, Kyung Min, Lee, Jeoung Eun, Park, Ji Eun, Kim, Hyunjin, Jang, Hee Yeon, Go, Minyeon, Lee, Dong Ryul, Shim, Sung Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452414/ https://www.ncbi.nlm.nih.gov/pubmed/34552632 http://dx.doi.org/10.1155/2021/5575185

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