VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation

OBJECTIVES: In glaucomatous eyes, the main aqueous humor (AH) outflow pathway is damaged by accumulated oxidative stress arising from the microenvironment, vascular dysregulation, and aging, which results in increased outflow resistance and ocular hypertension. Schlemm's canal (SC) serves as th...

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Detalles Bibliográficos
Autores principales: Lou, Xiaotong, Mou, Qianxue, Zhao, Bowen, Huang, Jingqiu, Yao, Ke, Luo, Zhaoxia, Ye, Meng, Hu, Yuanyuan, Duan, Qiming, Li, Xing, Wen, Zheng, Chen, Zhiqi, Zhang, Hong, Zhao, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452417/
https://www.ncbi.nlm.nih.gov/pubmed/34552687
http://dx.doi.org/10.1155/2021/9397960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452417/
https://www.ncbi.nlm.nih.gov/pubmed/34552687
http://dx.doi.org/10.1155/2021/9397960

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