Cargando…
VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation
OBJECTIVES: In glaucomatous eyes, the main aqueous humor (AH) outflow pathway is damaged by accumulated oxidative stress arising from the microenvironment, vascular dysregulation, and aging, which results in increased outflow resistance and ocular hypertension. Schlemm's canal (SC) serves as th...
Autores principales: | Lou, Xiaotong, Mou, Qianxue, Zhao, Bowen, Huang, Jingqiu, Yao, Ke, Luo, Zhaoxia, Ye, Meng, Hu, Yuanyuan, Duan, Qiming, Li, Xing, Wen, Zheng, Chen, Zhiqi, Zhang, Hong, Zhao, Yin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452417/ https://www.ncbi.nlm.nih.gov/pubmed/34552687 http://dx.doi.org/10.1155/2021/9397960 |
Ejemplares similares
-
Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia
por: VanderWyst, Saumya S., et al.
Publicado: (2011) -
Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm’s Canal Endothelia
por: Tam, Lawrence C. S., et al.
Publicado: (2017) -
VIP Induces Changes in the F-/G-Actin Ratio of Schlemm's Canal Endothelium via LRRK2 Transcriptional Regulation
por: Yan, Xiaoqin, et al.
Publicado: (2020) -
Morphology of the Trabecular Meshwork and Schlemm's Canal in Posner-Schlossman Syndrome
por: Yan, Xiaoqin, et al.
Publicado: (2022) -
Schlemm's canal: the outflow ‘vessel’
por: Lewczuk, Katarzyna, et al.
Publicado: (2021)