Hypoxia‐stimulated ATM activation regulates autophagy‐associated exosome release from cancer‐associated fibroblasts to promote cancer cell invasion

Cancer‐associated fibroblasts (CAFs) as a predominant cell component in the tumour microenvironment (TME) play an essential role in tumour progression. Our earlier studies revealed oxidized ATM activation in breast CAFs, which is independent of DNA double‐strand breaks (DSBs). Oxidized ATM has been...

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Detalles Bibliográficos
Autores principales: Xi, Lei, Peng, Meixi, Liu, Shuiqing, Liu, Yongcan, Wan, Xueying, Hou, Yixuan, Qin, Yilu, Yang, Liping, Chen, Shanchun, Zeng, Huan, Teng, Yong, Cui, Xiaojiang, Liu, Manran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452512/
https://www.ncbi.nlm.nih.gov/pubmed/34545708
http://dx.doi.org/10.1002/jev2.12146

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