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Patient-specific iPSC-derived endothelial cells reveal aberrant p38 MAPK signaling in atypical hemolytic uremic syndrome

Atypical hemolytic uremic syndrome (aHUS) is a rare disease associated with high morbidity and mortality. Existing evidence suggests that the central pathogenesis to aHUS might be endothelial cell damage. Nevertheless, the role of endothelial cell alterations in aHUS has not been well characterized...

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Detalles Bibliográficos
Autores principales: Zhou, Danni, Tan, Ying, Liu, Xiaoling, Tang, Ling, Wang, Hao, Shen, Jiaxi, Wang, Wei, Zhuang, Lenan, Tao, Juan, Su, Jun, Gong, Tingyu, Liu, Xiaorong, Liang, Ping, Yu, Feng, Zhao, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452517/
https://www.ncbi.nlm.nih.gov/pubmed/34388364
http://dx.doi.org/10.1016/j.stemcr.2021.07.011