Human stem cell-based retina on chip as new translational model for validation of AAV retinal gene therapy vectors

Gene therapies using adeno-associated viruses (AAVs) are among the most promising strategies to treat or even cure hereditary and acquired retinal diseases. However, the development of new efficient AAV vectors is slow and costly, largely because of the lack of suitable non-clinical models. By faith...

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Detalles Bibliográficos
Autores principales: Achberger, Kevin, Cipriano, Madalena, Düchs, Matthias J., Schön, Christian, Michelfelder, Stefan, Stierstorfer, Birgit, Lamla, Thorsten, Kauschke, Stefan G., Chuchuy, Johanna, Roosz, Julia, Mesch, Lena, Cora, Virginia, Pars, Selin, Pashkovskaia, Natalia, Corti, Serena, Hartmann, Sophia-Marie, Kleger, Alexander, Kreuz, Sebastian, Maier, Udo, Liebau, Stefan, Loskill, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452599/
https://www.ncbi.nlm.nih.gov/pubmed/34525384
http://dx.doi.org/10.1016/j.stemcr.2021.08.008

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