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Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling

Cellular events require the spatiotemporal interplay between actin assembly and actin disassembly. Yet, how different factors promote the integration of these two opposing processes is unclear. In particular, cellular monomeric (G)-actin is complexed with profilin, which inhibits spontaneous actin n...

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Detalles Bibliográficos
Autores principales: Grintsevich, Elena E., Ahmed, Giasuddin, Ginosyan, Anush A., Wu, Heng, Rich, Shannon K., Reisler, Emil, Terman, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452626/
https://www.ncbi.nlm.nih.gov/pubmed/34545088
http://dx.doi.org/10.1038/s41467-021-25781-3