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Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
Cellular events require the spatiotemporal interplay between actin assembly and actin disassembly. Yet, how different factors promote the integration of these two opposing processes is unclear. In particular, cellular monomeric (G)-actin is complexed with profilin, which inhibits spontaneous actin n...
Autores principales: | Grintsevich, Elena E., Ahmed, Giasuddin, Ginosyan, Anush A., Wu, Heng, Rich, Shannon K., Reisler, Emil, Terman, Jonathan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452626/ https://www.ncbi.nlm.nih.gov/pubmed/34545088 http://dx.doi.org/10.1038/s41467-021-25781-3 |
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