Cargando…

Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy

A cutting edge therapy for future immuno-oncology is targeting a new series of inhibitory receptors (IRs): LAG-3, TIM-3, and TIGIT. Both immunogenomic analyses and diagnostic platforms to distinguish candidates and predict good responders to these IR-related agents are vital in clinical pathology. B...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takamatsu, Kimiharu, Tanaka, Nobuyuki, Hakozaki, Kyohei, Takahashi, Ryohei, Teranishi, Yu, Murakami, Tetsushi, Kufukihara, Ryohei, Niwa, Naoya, Mikami, Shuji, Shinojima, Toshiaki, Sasaki, Takashi, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Kakimi, Kazuhiro, Kamatani, Takashi, Miya, Fuyuki, Tsunoda, Tatsuhiko, Aimono, Eriko, Nishihara, Hiroshi, Sawada, Kazuaki, Imamura, Takeshi, Mizuno, Ryuichi, Oya, Mototsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452744/ https://www.ncbi.nlm.nih.gov/pubmed/34545095 http://dx.doi.org/10.1038/s41467-021-25865-0

Ejemplares similares

Unique characteristics of tertiary lymphoid structures in kidney clear cell carcinoma: prognostic outcome and comparison with bladder cancer
por: Masuda, Tsukasa, et al.
Publicado: (2022)

Topologically associating domain underlies tissue specific expression of long intergenic non-coding RNAs
por: Hamba, Yu, et al.
Publicado: (2023)

Immune subtypes and neoantigen-related immune evasion in advanced colorectal cancer
por: Sugawara, Toshitaka, et al.
Publicado: (2022)

Quantification of multicellular colonization in tumor metastasis using exome‐sequencing data
por: Nishino, Jo, et al.
Publicado: (2020)

Can urologists introduce the concept of “oligometastasis” for metastatic bladder cancer after total cystectomy?
por: Ogihara, Koichiro, et al.
Publicado: (2017)

Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy
por: Cai, Letong, et al.
Publicado: (2023)

Correction: Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy
por: Cai, Letong, et al.
Publicado: (2023)

Accidental Hypothermia Treated by Hemodialysis in the Acute Phase: Three Case Reports and a Review of the Literature
por: Murakami, Tetsushi, et al.
Publicado: (2019)

Attenuation of Progressive Hearing Loss in DBA/2J Mice by Reagents that Affect Epigenetic Modifications Is Associated with Up-Regulation of the Zinc Importer Zip4
por: Mutai, Hideki, et al.
Publicado: (2015)

Integrative immunogenomic analysis of gastric cancer dictates novel immunological classification and the functional status of tumor‐infiltrating cells
por: Sato, Yasuyoshi, et al.
Publicado: (2020)

Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes
por: Hosoe, Jun, et al.
Publicado: (2021)

Gene expression dataset for whole cochlea of Macaca fascicularis
por: Mutai, Hideki, et al.
Publicado: (2018)

Tissue-Specific Expression of TIGIT, PD-1, TIM-3, and CD39 by γδ T Cells in Ovarian Cancer
por: Weimer, Pauline, et al.
Publicado: (2022)

Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: a case report
por: Hongo, Hiroshi, et al.
Publicado: (2020)

Gene expression profiling of DBA/2J mice cochleae treated with l-methionine and valproic acid
por: Miya, Fuyuki, et al.
Publicado: (2015)

Tim-3 signaling blockade with α-lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA-infected mice
por: Zhang, Yiwei, et al.
Publicado: (2019)

Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation
por: Tanaka, Yumiko, et al.
Publicado: (2023)

A case report of reversible generalized seizures in a patient with Waardenburg syndrome associated with a novel nonsense mutation in the penultimate exon of SOX10
por: Suzuki, Noriomi, et al.
Publicado: (2018)

Association between high immune activity and worse prognosis in uveal melanoma and low-grade glioma in TCGA transcriptomic data
por: Matsuo, Hitoshi, et al.
Publicado: (2022)

Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans
por: Mutai, Hideki, et al.
Publicado: (2020)

Expression of T-cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) in anaplastic thyroid carcinoma
por: Nakazawa, Tadao, et al.
Publicado: (2022)

Addition of anti-TIM3 or anti-TIGIT Antibodies to anti-PD1 Blockade Augments Human T cell Adoptive Cell Transfer
por: Martinez, Marina, et al.
Publicado: (2021)

Increased coexpression of PD-L1 and TIM3/TIGIT is associated with poor overall survival of patients with esophageal squamous cell carcinoma
por: Wang, Peipei, et al.
Publicado: (2021)

Bone Marrow-Resident Vδ1 T Cells Co-express TIGIT With PD-1, TIM-3 or CD39 in AML and Myeloma
por: Brauneck, Franziska, et al.
Publicado: (2021)

TIGIT(+) TIM-3(+) NK cells are correlated with NK cell exhaustion and disease progression in patients with hepatitis B virus‑related hepatocellular carcinoma
por: Yu, Lihua, et al.
Publicado: (2021)

TIGIT in cancer immunotherapy
por: Chauvin, Joe-Marc, et al.
Publicado: (2020)

Increased co-expression of TIM-3 with TIGIT or 2B4 on CD8+ T cells is associated with poor prognosis in locally advanced nasopharyngeal carcinoma
por: Xie, Xiaolin, et al.
Publicado: (2023)

The prediction models for postoperative overall survival and disease‐free survival in patients with breast cancer
por: Shigemizu, Daichi, et al.
Publicado: (2017)

A combination of targeted enrichment methodologies for whole-exome sequencing reveals novel pathogenic mutations
por: Miya, Fuyuki, et al.
Publicado: (2015)

A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation
por: Kosaka, Takeo, et al.
Publicado: (2019)

Prominent response to platinum‐based chemotherapy in a patient with BRCA2 mutant‐neuroendocrine prostate cancer and MDM2 amplification
por: Daimon, Tatsuaki, et al.
Publicado: (2021)

First successful case of platinum‐based chemotherapy for neuroendocrine prostate cancer with BRCA2 and PTEN alterations
por: Omura, Minami, et al.
Publicado: (2021)

Cytometric cell-based assays for anti-striational antibodies in myasthenia gravis with myositis and/or myocarditis
por: Kufukihara, Kenji, et al.
Publicado: (2019)

Different expression patterns of VISTA concurrent with PD-1, Tim-3, and TIGIT on T cell subsets in peripheral blood and bone marrow from patients with multiple myeloma
por: Huang, Shuxin, et al.
Publicado: (2022)

Genetic Profiling of Malignant Melanoma Arising from an Ovarian Mature Cystic Teratoma: A Case Report
por: Nakamura, Kohei, et al.
Publicado: (2021)

In Vitro Drug Sensitivity Tests to Predict Molecular Target Drug Responses in Surgically Resected Lung Cancer
por: Miyazaki, Ryohei, et al.
Publicado: (2016)

Correction: In Vitro Drug Sensitivity Tests to Predict Molecular Target Drug Responses in Surgically Resected Lung Cancer
por: Miyazaki, Ryohei, et al.
Publicado: (2016)

CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression
por: Yanai, Yoshinori, et al.
Publicado: (2020)

Immune Co-inhibitory Receptors CTLA-4, PD-1, TIGIT, LAG-3, and TIM-3 in Upper Tract Urothelial Carcinomas: A Large Cohort Study
por: Jin, Shengming, et al.
Publicado: (2023)

TIGIT-based immunotherapeutics in lung cancer
por: Patel, Akshay J, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gs2d9f7ad2jdp3gn4780voj6c8