Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development

Mutations in RAC1 allele are implicated in multiple brain tumors, indicating a rigorous control of Rac1 activity is required for neural tissue normal development and homeostasis. To understand how elevated Rac1 activity affects neural crest cells (NCCs) development, we have generated Rac1(CA);Wnt1-C...

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Detalles Bibliográficos
Autores principales: Gahankari, Apurva, Dong, Chunmin, Bartoletti, Garrett, Galazo, Maria, He, Fenglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452869/
https://www.ncbi.nlm.nih.gov/pubmed/34557485
http://dx.doi.org/10.3389/fcell.2021.704769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452869/
https://www.ncbi.nlm.nih.gov/pubmed/34557485
http://dx.doi.org/10.3389/fcell.2021.704769

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