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Dose-Effect/Toxicity of Bupleuri Radix on Chronic Unpredictable Mild Stress and Normal Rats Based on Liver Metabolomics
Depression, one of the most prevalent psychiatric diseases, affects the quality of life of millions of people. Studies have shown that the lower polar fraction of Bupleuri Radix (PBR) elicited therapeutic effects in chronic unpredictable mild stress (CUMS) rats. In contrast, comparatively mild liver...
Autores principales: | Wang, Peng, Gao, Xiaoxia, Liang, Meili, Fang, Yuan, Jia, Jinping, Tian, Junsheng, Li, Zhenyu, Qin, Xuemei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452938/ https://www.ncbi.nlm.nih.gov/pubmed/34557088 http://dx.doi.org/10.3389/fphar.2021.627451 |
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