Cargando…

Bradykinin Protects Human Endothelial Progenitor Cells from High-Glucose-Induced Senescence through B2 Receptor-Mediated Activation of the Akt/eNOS Signalling Pathway

BACKGROUND: Circulating endothelial progenitor cells (EPCs) play important roles in vascular repair. However, the mechanisms of high-glucose- (HG-) induced cord blood EPC senescence and the role of B2 receptor (B2R) remain unknown. METHODS: Cord blood samples from 26 patients with gestational diabet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yuehuan, Fu, Cong, Li, Bing, Liu, Chang, He, Zhi, Li, Xing-Er, Wang, Ailing, Ma, Genshan, Yao, Yuyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452971/ https://www.ncbi.nlm.nih.gov/pubmed/34557552 http://dx.doi.org/10.1155/2021/6626627

Ejemplares similares

Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/EGFR/RB signal pathways
por: Fu, Cong, et al.
Publicado: (2015)

Bradykinin Preconditioning Improves Therapeutic Potential of Human Endothelial Progenitor Cells in Infarcted Myocardium
por: Sheng, Zulong, et al.
Publicado: (2013)

Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca(2+) Levels and eNOS Phosphorylation at Ser(1179)
por: Thebault, Stéphanie, et al.
Publicado: (2011)

Salvianic Acid A Regulates High-Glucose-Treated Endothelial Progenitor Cell Dysfunction via the AKT/Endothelial Nitric Oxide Synthase (eNOS) Pathway
por: Guan, Yanhua, et al.
Publicado: (2021)

Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling
por: Zhu, Cuicui, et al.
Publicado: (2017)

Rosuvastatin Enhances Angiogenesis via eNOS-Dependent Mobilization of Endothelial Progenitor Cells
por: Zhou, Junlan, et al.
Publicado: (2013)

Icariin reduces high glucose-induced endothelial progenitor cell dysfunction via inhibiting the p38/CREB pathway and activating the Akt/eNOS/NO pathway
por: Chen, Sisi, et al.
Publicado: (2019)

Hydrogen Repairs LPS-Induced Endothelial Progenitor Cells Injury via PI3K/AKT/eNOS Pathway
por: Mu, Qingjie, et al.
Publicado: (2022)

Neovasculogenic effect of 11,12-epoxyeicosatrienoic acid involves the Akt/eNOS signaling pathways in human endothelial progenitor cells
por: Hung, Hung-Chang, et al.
Publicado: (2022)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway
por: Zhang, Zhiyong, et al.
Publicado: (2020)

Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells
por: Niu, Haiming, et al.
Publicado: (2023)

Aliskiren Improved the Endothelial Repair Capacity of Endothelial Progenitor Cells from Patients with Hypertension via the Tie2/PI3k/Akt/eNOS Signalling Pathway
por: Yao, Shun, et al.
Publicado: (2020)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway [Corrigendum]
Publicado: (2020)

Total flavonoids from Astragalus alleviate endothelial dysfunction by activating the Akt/eNOS pathway
por: Liu, Qian, et al.
Publicado: (2017)

Naringenin upregulates GTPCH1/eNOS to ameliorate high glucose-induced retinal endothelial cell injury
por: Xue, Bing, et al.
Publicado: (2022)

Tissue Kallikrein-Modified Human Endothelial Progenitor Cell Implantation Improves Cardiac Function via Enhanced Activation of Akt and Increased Angiogenesis
por: Yao, Yuyu, et al.
Publicado: (2013)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling
por: Wang, Jianhua, et al.
Publicado: (2023)

The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
por: Alghanem, Ahmad F, et al.
Publicado: (2021)

Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway
por: Zhou, Caixia, et al.
Publicado: (2022)

Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress
por: Mahmoud, Ayman M., et al.
Publicado: (2017)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway
por: Lei, Wenhua, et al.
Publicado: (2021)

Endothelial cell-specific loss of eNOS differentially affects endothelial function
por: Bu, Shuhan, et al.
Publicado: (2022)

AKT/eNOS signaling module functions as a potential feedback loop in the growth hormone signaling pathway
por: Li, Cong-Jun, et al.
Publicado: (2009)

Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice
por: Yu, Jia-Wen, et al.
Publicado: (2016)

Abnormal phosphorylation of Tie2/Akt/eNOS signaling pathway and decreased number or function of circulating endothelial progenitor cells in prehypertensive premenopausal women with diabetes mellitus
por: Zeng, Haitao, et al.
Publicado: (2016)

Extensive Ethnogenomic Diversity of Endothelial Nitric Oxide Synthase (eNOS) Polymorphisms
por: Thomas, Bolaji N., et al.
Publicado: (2013)

Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells
por: Chen, Zhenlong, et al.
Publicado: (2018)

Sex-specific eNOS activity and function in human endothelial cells
por: Cattaneo, Maria Grazia, et al.
Publicado: (2017)

Hyperlipidemia attenuates the mobilization of endothelial progenitor cells induced by acute myocardial ischemia via VEGF/eNOS/NO/MMP-9 pathway
por: Zhou, Jidong, et al.
Publicado: (2022)

Thyrotropin Regulates eNOS Expression in the Endothelium by PGRN Through Akt Pathway
por: Jiang, Fengwei, et al.
Publicado: (2018)

Acute Mechanical Stretch Promotes eNOS Activation in Venous Endothelial Cells Mainly via PKA and Akt Pathways
por: Hu, Zhenqian, et al.
Publicado: (2013)

Crocetin promotes angiogenesis in human endothelial cells through PI3K-Akt-eNOS signaling pathway
por: Nasirzadeh, Mahdieh, et al.
Publicado: (2019)

Endothelial S1pr1 regulates pressure overload‐induced cardiac remodelling through AKT‐eNOS pathway
por: Liu, Xiuxiang, et al.
Publicado: (2019)

Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway
por: Gu, Yang-Yang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qier83o0vgc2ef46muo8roh4mn