Cargando…

The Role of Thioredoxin/Peroxiredoxin in the β-Cell Defense Against Oxidative Damage

Oxidative stress is hypothesized to play a role in pancreatic β-cell damage, potentially contributing to β-cell dysfunction and death in both type 1 and type 2 diabetes. Oxidative stress arises when naturally occurring reactive oxygen species (ROS) are produced at levels that overwhelm the antioxida...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stancill, Jennifer S., Corbett, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453158/ https://www.ncbi.nlm.nih.gov/pubmed/34557160 http://dx.doi.org/10.3389/fendo.2021.718235

Ejemplares similares

A thioredoxin-dependent peroxiredoxin Q from Corynebacterium glutamicum plays an important role in defense against oxidative stress
por: Su, Tao, et al.
Publicado: (2018)

Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function
por: Stancill, Jennifer S, et al.
Publicado: (2022)

A Novel Thioredoxin-Dependent Peroxiredoxin (TPx-Q) Plays an Important Role in Defense Against Oxidative Stress and Is a Possible Drug Target in Babesia microti
por: Zhang, Houshuang, et al.
Publicado: (2020)

The Roles of Peroxiredoxin and Thioredoxin in Hydrogen Peroxide Sensing and in Signal Transduction
por: Netto, Luis E. S., et al.
Publicado: (2016)

Thioredoxin 1 protects astrocytes from oxidative stress by maintaining peroxiredoxin activity
por: WANG, MENGFEI, et al.
Publicado: (2016)

Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1
por: Dorey, Amber, et al.
Publicado: (2021)

Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma
por: Cha, Mee-Kyung, et al.
Publicado: (2009)

Expression of thioredoxin 1 and peroxiredoxins in squamous cervical carcinoma and its predictive role in NACT
por: Zhu, Haiyan, et al.
Publicado: (2019)

Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury
por: Forred, Benjamin J., et al.
Publicado: (2017)

β-cell–selective inhibition of DNA damage response signaling by nitric oxide is associated with an attenuation in glucose uptake
por: Yeo, Chay Teng, et al.
Publicado: (2023)

A Peroxiredoxin Promotes H(2)O(2) Signaling and Oxidative Stress Resistance by Oxidizing a Thioredoxin Family Protein
por: Brown, Jonathon D., et al.
Publicado: (2013)

Regulation of ATR-dependent DNA damage response by nitric oxide
por: Yeo, Chay Teng, et al.
Publicado: (2021)

The chloroplast 2-cysteine peroxiredoxin functions as thioredoxin oxidase in redox regulation of chloroplast metabolism
por: Vaseghi, Mohamad-Javad, et al.
Publicado: (2018)

Peroxiredoxin 6 Modulates Insulin Secretion and Beta Cell Death via a Mitochondrial Dynamic Network
por: Pacifici, Francesca, et al.
Publicado: (2022)

Cytokine and Nitric Oxide-Dependent Gene Regulation in Islet Endocrine and Nonendocrine Cells
por: Stancill, Jennifer S, et al.
Publicado: (2021)

Editorial: Understanding the gene expression of β cell dysfunction in diabetes
por: Sjöholm, Åke, et al.
Publicado: (2022)

Peroxiredoxin V Protects against UVB-Induced Damage of Keratinocytes
por: Kim, Sin Ri, et al.
Publicado: (2023)

Peroxiredoxin 2: An Important Element of the Antioxidant Defense of the Erythrocyte
por: Sadowska-Bartosz, Izabela, et al.
Publicado: (2023)

Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants
por: Ragu, Sandrine, et al.
Publicado: (2014)

Exploring the Functional Relationship between y-Type Thioredoxins and 2-Cys Peroxiredoxins in Arabidopsis Chloroplasts
por: Jurado-Flores, Ana, et al.
Publicado: (2020)

Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress
por: Tasaki, Eisuke, et al.
Publicado: (2017)

Peroxiredoxin 4 protects against ovarian ageing by ameliorating d-galactose-induced oxidative damage in mice
por: Liang, Xiuru, et al.
Publicado: (2020)

Typical 2-Cys Peroxiredoxins as a Defense Mechanism against Metal-Induced Oxidative Stress in the Solitary Ascidian Ciona robusta
por: Drago, Laura, et al.
Publicado: (2021)

Role of peroxiredoxin of the AhpC/TSA family in antioxidant defense mechanisms of Francisella tularensis
por: Alharbi, Arwa, et al.
Publicado: (2019)

De novo assembly and functional annotation of blood transcriptome of loggerhead turtle, and in silico characterization of peroxiredoxins and thioredoxins
por: Hernández-Fernández, Javier, et al.
Publicado: (2021)

Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways
por: Zhou, Feng, et al.
Publicado: (2018)

Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage
por: Tulsawani, Rajkumar, et al.
Publicado: (2010)

N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells
por: Nord, Joshua A., et al.
Publicado: (2022)

The Functional Relationship between NADPH Thioredoxin Reductase C, 2-Cys Peroxiredoxins, and m-Type Thioredoxins in the Regulation of Calvin–Benson Cycle and Malate-Valve Enzymes in Arabidopsis
por: Delgado-Requerey, Víctor, et al.
Publicado: (2023)

The contribution of NADPH thioredoxin reductase C (NTRC) and sulfiredoxin to 2-Cys peroxiredoxin overoxidation in Arabidopsis thaliana chloroplasts
por: Puerto-Galán, Leonor, et al.
Publicado: (2015)

Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry
por: Horie, Kayo, et al.
Publicado: (2018)

The Role of Peroxiredoxin 6 in Cell Signaling
por: Arevalo, José A., et al.
Publicado: (2018)

Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types
por: Selvaggio, Gianluca, et al.
Publicado: (2017)

The role of peroxiredoxins in cancer
por: Nicolussi, Arianna, et al.
Publicado: (2017)

Preoperative circulating peroxiredoxin 1 levels as a predictor of non-alcoholic fatty liver disease remission after laparoscopic bariatric surgery
por: Cheng, Xiaoyun, et al.
Publicado: (2022)

The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cells
por: Zhao, Fang, et al.
Publicado: (2012)

β-Hydroxybutyrate, a Ketone Body, Potentiates the Antioxidant Defense via Thioredoxin 1 Upregulation in Cardiomyocytes
por: Oka, Shin-ichi, et al.
Publicado: (2021)

KH176 Safeguards Mitochondrial Diseased Cells from Redox Stress-Induced Cell Death by Interacting with the Thioredoxin System/Peroxiredoxin Enzyme Machinery
por: Beyrath, Julien, et al.
Publicado: (2018)

The protective role of nutritional antioxidants against oxidative stress in thyroid disorders
por: Macvanin, Mirjana T., et al.
Publicado: (2023)

Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and aging
por: Oberacker, Tina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_agut454gghmun7r8c0rqcqi463