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Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release

The evolutionarily conserved Hedgehog (Hh) signaling pathway is crucial for programmed cell differentiation and proliferation. Dispatched (Disp) is a 12-transmembrane protein that plays a critical role in the Hedgehog (Hh) signaling pathway by releasing the dually lipidated ligand HhN from the membr...

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Detalles Bibliográficos
Autores principales:	Luo, Yitian, Wan, Guoyue, Zhou, Xuan, Wang, Qiuwen, Zhang, Yunbin, Bao, Juan, Cong, Yao, Zhao, Yun, Li, Dianfan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453165/ https://www.ncbi.nlm.nih.gov/pubmed/34557519 http://dx.doi.org/10.3389/fmolb.2021.701826

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