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Clinical Relevance of Serum Kyn/Trp Ratio and Basal and IFNγ-Upregulated IDO1 Expression in Peripheral Monocytes in Early Stage Melanoma

Immune escape is an early phenomenon in cancer development/progression. Indoleamine 2,3-dioxygenase 1 (IDO1) is a normal endogenous mechanism of acquired peripheral immune tolerance and may therefore be tumor-promoting. This study investigated the clinical relevance of IDO1 expression by immune cell...

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Detalles Bibliográficos
Autores principales:	Meireson, Annabel, Ferdinande, Liesbeth, Haspeslagh, Marc, Hennart, Benjamin, Allorge, Delphine, Ost, Piet, Sundahl, Nora, Spaas, Mathieu, Demeyer, Annelies, Brochez, Lieve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453201/ https://www.ncbi.nlm.nih.gov/pubmed/34557196 http://dx.doi.org/10.3389/fimmu.2021.736498

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