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Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis

JAK/STAT plays an important role in cytokine signal transduction and it is potentially involved in the proinflammatory response during the early phase of severe acute pancreatitis (SAP). However, whether JAK2 activity is upregulated and whether JAK2 inhibition plays a role in the maintenance of panc...

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Detalles Bibliográficos
Autores principales:	Qiu, Zhaolei, Xu, Feng, Wang, Zhenjie, Yang, Peng, Bu, Zhang, Cheng, Feng, Jiang, Hai, Li, Lei, Zhang, Fulong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453217/ https://www.ncbi.nlm.nih.gov/pubmed/34584986 http://dx.doi.org/10.1016/j.bbrep.2021.101133

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