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STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma
Lung cancer is the second leading cause of cancer death worldwide and is strongly associated with cisplatin resistance. The transcription factor signal transducer and activator of transcription 3 (STAT3) is constitutively activated in cancer cells and coordinates critical cellular processes as survi...
Autores principales: | Morelli, Ana Paula, Tortelli, Tharcísio Citrângulo, Mancini, Mariana Camargo Silva, Pavan, Isadora Carolina Betim, Silva, Luiz Guilherme Salvino, Severino, Matheus Brandemarte, Granato, Daniela Campos, Pestana, Nathalie Fortes, Ponte, Luis Gustavo Saboia, Peruca, Guilherme Francisco, Pauletti, Bianca Alves, dos Santos, Daniel Francisco Guimarães, de Moura, Leandro Pereira, Bezerra, Rosângela Maria Neves, Leme, Adriana Franco Paes, Chammas, Roger, Simabuco, Fernando Moreira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453219/ https://www.ncbi.nlm.nih.gov/pubmed/34543857 http://dx.doi.org/10.1016/j.neo.2021.08.003 |
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