Astragaloside IV Protects from PM2.5-Induced Lung Injury by Regulating Autophagy via Inhibition of PI3K/Akt/mTOR Signaling in vivo and in vitro

INTRODUCTION: Prolonged exposure to air polluted with airborne fine particulate matter (PM2.5) can increase respiratory disease risk. Astragaloside IV (AS-IV) is one of the main bioactive substances in the traditional Chinese medicinal herb, Astragalus membranaceus Bunge. AS-IV has numerous pharmaco...

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Detalles Bibliográficos
Autores principales: Pei, Caixia, Wang, Fei, Huang, Demei, Shi, Shihua, Wang, Xiaomin, Wang, Yilan, Li, Shuiqin, Wu, Yongcan, Wang, Zhenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453246/
https://www.ncbi.nlm.nih.gov/pubmed/34557015
http://dx.doi.org/10.2147/JIR.S312167

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