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Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions

COVID-19 pandemic has imposed many challenges on paediatric liver transplantation (PLT) services and has necessitated several adaptations in different stages of the process to ensure transplant centres can still deliver the proposed services in addition to protecting patients and staff against infec...

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Autores principales: Alnagar, Amr, Ruth, Nicola, Elsharif, Mohamed, Bici, Kejd, Shawky, Ahmed, Kelly, Deirdre, Attia, Magdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453461/
https://www.ncbi.nlm.nih.gov/pubmed/34568760
http://dx.doi.org/10.1007/s42399-021-01050-8
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author Alnagar, Amr
Ruth, Nicola
Elsharif, Mohamed
Bici, Kejd
Shawky, Ahmed
Kelly, Deirdre
Attia, Magdy
author_facet Alnagar, Amr
Ruth, Nicola
Elsharif, Mohamed
Bici, Kejd
Shawky, Ahmed
Kelly, Deirdre
Attia, Magdy
author_sort Alnagar, Amr
collection PubMed
description COVID-19 pandemic has imposed many challenges on paediatric liver transplantation (PLT) services and has necessitated several adaptations in different stages of the process to ensure transplant centres can still deliver the proposed services in addition to protecting patients and staff against infection. This review article digs through the current literature to clarify the challenges imposed by SARS-CoV2 on PLT centres globally. It provides an overview of current practice as well as suggestions from experts in the field to overcome multiple obstacles. In paediatrics, the reaction to SARS-CoV2 may be less severe than that seen in the adult population, but this can change in view of newly discovered virus strains. Response of transplant centres to the current pandemic was variable depending on the anticipated risk and available resources. Telemedicine has helped PLT programmes to continue their activities while protecting patients, as well as staff against the risk of SARS-CoV2 virus. Further studies are needed to guide immunosuppression management in post-transplant infected candidates; answering this critical question will help PLT centres solve this dilemma.
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spelling pubmed-84534612021-09-21 Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions Alnagar, Amr Ruth, Nicola Elsharif, Mohamed Bici, Kejd Shawky, Ahmed Kelly, Deirdre Attia, Magdy SN Compr Clin Med Review COVID-19 pandemic has imposed many challenges on paediatric liver transplantation (PLT) services and has necessitated several adaptations in different stages of the process to ensure transplant centres can still deliver the proposed services in addition to protecting patients and staff against infection. This review article digs through the current literature to clarify the challenges imposed by SARS-CoV2 on PLT centres globally. It provides an overview of current practice as well as suggestions from experts in the field to overcome multiple obstacles. In paediatrics, the reaction to SARS-CoV2 may be less severe than that seen in the adult population, but this can change in view of newly discovered virus strains. Response of transplant centres to the current pandemic was variable depending on the anticipated risk and available resources. Telemedicine has helped PLT programmes to continue their activities while protecting patients, as well as staff against the risk of SARS-CoV2 virus. Further studies are needed to guide immunosuppression management in post-transplant infected candidates; answering this critical question will help PLT centres solve this dilemma. Springer International Publishing 2021-09-21 2021 /pmc/articles/PMC8453461/ /pubmed/34568760 http://dx.doi.org/10.1007/s42399-021-01050-8 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Alnagar, Amr
Ruth, Nicola
Elsharif, Mohamed
Bici, Kejd
Shawky, Ahmed
Kelly, Deirdre
Attia, Magdy
Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title_full Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title_fullStr Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title_full_unstemmed Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title_short Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions
title_sort paediatric liver transplantation during covid-19 pandemic: lessons learned and unanswered questions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453461/
https://www.ncbi.nlm.nih.gov/pubmed/34568760
http://dx.doi.org/10.1007/s42399-021-01050-8
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