New Paradigm in NKT Cell Antigens: MCS‐0208 (2‐(Hydroxymethyl)phenylthio‐phytoceramide) – an Aryl‐Phytoceramide Compound with a Single Hydroxyl Group Stimulates NKT Cells

Natural Killer T (NKT) cells play an important role in the immune response and can be activated by glycolipids presented by CD1d protein. We present MCS‐0208, an unprecedented arylthioether‐phytoceramide able to induce potent invariant NKT (iNKT) cell activation, notably when tested in human iNKT ce...

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Detalles Bibliográficos
Autores principales: Borràs‐Tudurí, Roser, Alcaide, Anna, Aspeslag, Sandrine, Usero, Lorena, Serra, Carmen, Roura‐Mir, Carme, Elewaut, Dirk, Llebaria, Amadeu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453509/
https://www.ncbi.nlm.nih.gov/pubmed/33821540
http://dx.doi.org/10.1002/cmdc.202000992

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