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Discovery of Nonracemic Amisulpride to Maximize Benefit/Risk of 5‐HT7 and D2 Receptor Antagonism for the Treatment of Mood Disorders

In contrast to the dose‐occupancy relationship in the treatment of schizophrenia, the minimal effective level of dopamine receptor 2 (D2R) blockade for antipsychotics in the treatment of bipolar depression is unknown. Lower doses aimed at reducing extrapyramidal side effects must be balanced against...

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Detalles Bibliográficos
Autores principales:	Hopkins, Seth C., Wilkinson, Scott, Corriveau, Taryn J., Nishikawa, Hiroyuki, Nakamichi, Keiko, Loebel, Antony, Koblan, Kenneth S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453756/ https://www.ncbi.nlm.nih.gov/pubmed/33961287 http://dx.doi.org/10.1002/cpt.2282

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