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CLRM-09. INCORPORATING EXTERNAL CONTROL ARM IN MDNA55 RECURRENT GLIOBLASTOMA REGISTRATION TRIAL
BACKGROUND: Drug development in recurrent glioblastoma multiforme (rGBM) is challenging. For randomized controlled trials (RCTs) short survival horizons and limited life-prolonging treatment options may delay accrual and introduce bias through differential dropout of control patients. Comparing resu...
Autores principales: | Davi, Ruthanna, Majumdar, Antara, Bexon, Martin, Butowski, Nicholas, Chandhasin, Chandtip, Coello, Melissa, Das, Sunit, Merchant, Fahar, Merchant, Nina, Reardon, David, Roessner, Martin, Sampson, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453772/ http://dx.doi.org/10.1093/noajnl/vdab112.008 |
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