Total Synthesis and Bioactivity Mapping of Geodiamolide H

The first total synthesis of the actin‐stabilizing marine natural product geodiamolide H was achieved. Solid‐phase based peptide assembly paired with scalable stereoselective syntheses of polyketide building blocks and an optimized esterification set the stage for investigating the key ring‐closing...

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Detalles Bibliográficos
Autores principales: Nasufović, Veselin, Küllmer, Florian, Bößneck, Johanna, Dahse, Hans‐Martin, Görls, Helmar, Bellstedt, Peter, Stallforth, Pierre, Arndt, Hans‐Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453818/
https://www.ncbi.nlm.nih.gov/pubmed/34032329
http://dx.doi.org/10.1002/chem.202100989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453818/
https://www.ncbi.nlm.nih.gov/pubmed/34032329
http://dx.doi.org/10.1002/chem.202100989

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