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Total Synthesis and Bioactivity Mapping of Geodiamolide H
The first total synthesis of the actin‐stabilizing marine natural product geodiamolide H was achieved. Solid‐phase based peptide assembly paired with scalable stereoselective syntheses of polyketide building blocks and an optimized esterification set the stage for investigating the key ring‐closing...
Autores principales: | Nasufović, Veselin, Küllmer, Florian, Bößneck, Johanna, Dahse, Hans‐Martin, Görls, Helmar, Bellstedt, Peter, Stallforth, Pierre, Arndt, Hans‐Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453818/ https://www.ncbi.nlm.nih.gov/pubmed/34032329 http://dx.doi.org/10.1002/chem.202100989 |
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