Neurodegeneration in Hepatic and Neurologic Wilson’s Disease

Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was...

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Autores principales: Viveiros, André, Beliveau, Vincent, Panzer, Marlene, Schaefer, Benedikt, Glodny, Bernhard, Henninger, Benjamin, Tilg, Herbert, Zoller, Heinz, Scherfler, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Clinical Observations in Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453945/
https://www.ncbi.nlm.nih.gov/pubmed/33316133
http://dx.doi.org/10.1002/hep.31681
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author Viveiros, André
Beliveau, Vincent
Panzer, Marlene
Schaefer, Benedikt
Glodny, Bernhard
Henninger, Benjamin
Tilg, Herbert
Zoller, Heinz
Scherfler, Christoph
author_facet Viveiros, André
Beliveau, Vincent
Panzer, Marlene
Schaefer, Benedikt
Glodny, Bernhard
Henninger, Benjamin
Tilg, Herbert
Zoller, Heinz
Scherfler, Christoph
author_sort Viveiros, André
collection PubMed
description Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was present in neurological WD. Cerebellar atrophy was observed in hepatic WD without neurological symptoms.
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spelling pubmed-84539452021-09-27 Neurodegeneration in Hepatic and Neurologic Wilson’s Disease Viveiros, André Beliveau, Vincent Panzer, Marlene Schaefer, Benedikt Glodny, Bernhard Henninger, Benjamin Tilg, Herbert Zoller, Heinz Scherfler, Christoph Hepatology Clinical Observations in Hepatology Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was present in neurological WD. Cerebellar atrophy was observed in hepatic WD without neurological symptoms. John Wiley and Sons Inc. 2021-05-06 2021-08 /pmc/articles/PMC8453945/ /pubmed/33316133 http://dx.doi.org/10.1002/hep.31681 Text en © 2020 The Authors. Hepatology published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Clinical Observations in Hepatology
Viveiros, André
Beliveau, Vincent
Panzer, Marlene
Schaefer, Benedikt
Glodny, Bernhard
Henninger, Benjamin
Tilg, Herbert
Zoller, Heinz
Scherfler, Christoph
Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title_full Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title_fullStr Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title_full_unstemmed Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title_short Neurodegeneration in Hepatic and Neurologic Wilson’s Disease
title_sort neurodegeneration in hepatic and neurologic wilson’s disease
topic Clinical Observations in Hepatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453945/
https://www.ncbi.nlm.nih.gov/pubmed/33316133
http://dx.doi.org/10.1002/hep.31681
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