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Total Synthesis of Aetokthonotoxin, the Cyanobacterial Neurotoxin Causing Vacuolar Myelinopathy

Aetokthonotoxin has recently been identified as the cyanobacterial neurotoxin causing Vacuolar Myelinopathy, a fatal neurologic disease, spreading through a trophic cascade and affecting birds of prey such as the bald eagle in the USA. Here, we describe the total synthesis of this specialized metabo...

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Detalles Bibliográficos
Autores principales: Ricardo, Manuel G., Schwark, Markus, Llanes, Dayma, Niedermeyer, Timo H. J., Westermann, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453946/
https://www.ncbi.nlm.nih.gov/pubmed/34081364
http://dx.doi.org/10.1002/chem.202101848