From Natural Methylation to Versatile Alkylations Using Halide Methyltransferases

Halide methyltransferases (HMTs) enable the enzymatic synthesis of S‐adenosyl‐l‐methionine (SAM) from S‐adenosyl‐l‐homocysteine (SAH) and methyl iodide. Characterisation of a range of naturally occurring HMTs and subsequent protein engineering led to HMT variants capable of synthesising ethyl, propy...

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Detalles Bibliográficos
Autores principales: Tang, Qingyun, Pavlidis, Ioannis V., Badenhorst, Christoffel P. S., Bornscheuer, Uwe T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Concepts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453949/
https://www.ncbi.nlm.nih.gov/pubmed/33890381
http://dx.doi.org/10.1002/cbic.202100153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453949/
https://www.ncbi.nlm.nih.gov/pubmed/33890381
http://dx.doi.org/10.1002/cbic.202100153

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