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IL-1β and HMGB1 are anti-neurogenic to endogenous neural stem cells in the sclerotic epileptic human hippocampus

BACKGROUND: The dentate gyrus exhibits life-long neurogenesis of granule-cell neurons, supporting hippocampal dependent learning and memory. Both temporal lobe epilepsy patients and animal models frequently have hippocampal-dependent learning and memory difficulties and show evidence of reduced neur...

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Detalles Bibliográficos
Autores principales:	Zaben, Malik, Haan, Niels, Sharouf, Feras, Ahmed, Aminul, Sundstrom, Lars E., Gray, William P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454003/ https://www.ncbi.nlm.nih.gov/pubmed/34548070 http://dx.doi.org/10.1186/s12974-021-02265-1

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