β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer

BACKGROUND: Oncolytic viruses (OVs) are considered a promising therapeutic alternative for cancer. However, OVs could activate the host innate immunity, then impair the viral propagation in tumor cells. In this study, we explored the effect of propranolol, a non-selective β-blocker, on the antitumor...

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Detalles Bibliográficos
Autores principales: Hu, Jiali, Lu, Ruitao, Zhang, Yu, Li, Wei, Hu, Qian, Chen, Cuiyu, Liu, Zhaoqian, Zhang, Wei, Chen, Ling, Xu, Ran, Luo, Jia, McLeod, Howard L., He, Yijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454049/
https://www.ncbi.nlm.nih.gov/pubmed/34544479
http://dx.doi.org/10.1186/s13578-021-00687-1

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