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Inhibitory immune checkpoints PDCD-1 and LAG-3 hypermethylation may reduce the risk of colorectal cancer

BACKGROUND: Changes in DNA methylation of immunosuppressive checkpoints may impact express and consequently affect antigen processing and presentation by tumor cells and facilitates evasion of immunosurveillance and lead to colorectal cancer (CRC). This study is to investigate the effect of PDCD-1,...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuanyuan, zhang, Lei, Sun, Hongru, Liu, Ying, Xu, Jing, Huang, Hao, Fu, Jinming, Zhang, Ding, Tian, Tian, Zhao, Yashuang, Wang, Guiyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454079/ https://www.ncbi.nlm.nih.gov/pubmed/34544358 http://dx.doi.org/10.1186/s10020-021-00373-5

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