Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure

BACKGROUND: The identification of endogenous signals that lead to microglial activation is a key step in understanding neuroinflammatory cascades. As ATP release accompanies mechanical strain to neural tissue, and as the P2X7 receptor for ATP is expressed on microglial cells, we examined the morphol...

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Detalles Bibliográficos
Autores principales: Campagno, Keith E., Lu, Wennan, Jassim, Assraa Hassan, Albalawi, Farraj, Cenaj, Aurora, Tso, Huen-Yee, Clark, Sophia P., Sripinun, Puttipong, Gómez, Néstor Más, Mitchell, Claire H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454080/
https://www.ncbi.nlm.nih.gov/pubmed/34544431
http://dx.doi.org/10.1186/s12974-021-02251-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454080/
https://www.ncbi.nlm.nih.gov/pubmed/34544431
http://dx.doi.org/10.1186/s12974-021-02251-7

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