Cargando…

The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation

BACKGROUND: Microglia cells represent the resident innate immune cells of the retina and are important for retinal development and tissue homeostasis. However, dysfunctional microglia can have a negative impact on the structural and functional integrity of the retina under native and pathological co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Peipei, Schlecht, Anja, Wolf, Julian, Boneva, Stefaniya, Laich, Yannik, Koch, Jana, Ludwig, Franziska, Boeck, Myriam, Thien, Adrian, Härdtner, Carmen, Kierdorf, Katrin, Agostini, Hansjürgen, Schlunck, Günther, Prinz, Marco, Hilgendorf, Ingo, Wieghofer, Peter, Lange, Clemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454118/ https://www.ncbi.nlm.nih.gov/pubmed/34544421 http://dx.doi.org/10.1186/s12974-021-02230-y

Ejemplares similares

Immunosenescence in Choroidal Neovascularization (CNV)—Transcriptional Profiling of Naïve and CNV-Associated Retinal Myeloid Cells during Aging
por: Schlecht, Anja, et al.
Publicado: (2021)

Transcriptional Profiling Uncovers Human Hyalocytes as a Unique Innate Immune Cell Population
por: Boneva, Stefaniya Konstantinova, et al.
Publicado: (2020)

Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation
por: Schlecht, Anja, et al.
Publicado: (2022)

Secreted Phosphoprotein 1 Expression in Retinal Mononuclear Phagocytes Links Murine to Human Choroidal Neovascularization
por: Schlecht, Anja, et al.
Publicado: (2021)

Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives
por: Tenbrock, Louis, et al.
Publicado: (2021)

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations
por: Wolf, Julian, et al.
Publicado: (2022)

In-Depth Molecular Profiling Specifies Human Retinal Microglia Identity
por: Wolf, Julian, et al.
Publicado: (2022)

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy
por: Laich, Yannik, et al.
Publicado: (2022)

In-Depth Molecular Characterization of Neovascular Membranes Suggests a Role for Hyalocyte-to-Myofibroblast Transdifferentiation in Proliferative Diabetic Retinopathy
por: Boneva, Stefaniya Konstantinova, et al.
Publicado: (2021)

Welche Bedeutung hat die Bindehaut als möglicher Übertragungsweg für eine SARS-CoV-2-Infektion?
por: Lange, Clemens, et al.
Publicado: (2020)

What is the significance of the conjunctiva as a potential transmission route for SARS-CoV-2 infections?
por: Lange, Clemens, et al.
Publicado: (2020)

3′ MACE RNA-sequencing allows for transcriptome profiling in human tissue samples after long-term storage
por: Boneva, Stefaniya, et al.
Publicado: (2020)

Transcriptional characterization of conjunctival melanoma identifies the cellular tumor microenvironment and prognostic gene signatures
por: Wolf, Julian, et al.
Publicado: (2020)

Expression of the COVID‐19 receptor ACE2 in the human conjunctiva
por: Lange, Clemens, et al.
Publicado: (2020)

Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing
por: Wolf, Julian, et al.
Publicado: (2022)

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single‐cell profiling
por: Wieghofer, Peter, et al.
Publicado: (2021)

Imaging mass cytometry for high-dimensional tissue profiling in the eye
por: Schlecht, Anja, et al.
Publicado: (2021)

MACE RNA sequencing analysis of conjunctival squamous cell carcinoma and papilloma using formalin-fixed paraffin-embedded tumor tissue
por: Boneva, Stefaniya, et al.
Publicado: (2020)

Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation
por: Fernández-Robredo, Patricia, et al.
Publicado: (2017)

Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation
por: González-Zamora, Jorge, et al.
Publicado: (2022)

Effect of Intravitreal Ranibizumab in the Treatment of Peripapillary Choroidal Neovascularisation
por: Hamoudi, Hassan, et al.
Publicado: (2011)

Macular vortex vein with choroidal neovascularisation in pathologic myopia
por: Schouten, Ike M, et al.
Publicado: (2019)

Myopic choroidal neovascularisation: current concepts and update on clinical management
por: Wong, Tien Y, et al.
Publicado: (2015)

Pilot study of ziv-aflibercept in myopic choroidal neovascularisation patients
por: Nawar, Amin E., et al.
Publicado: (2020)

Expression of purinergic receptors on microglia in the animal model of choroidal neovascularisation
por: Li, Lu, et al.
Publicado: (2021)

Aflibercept as primary treatment for myopic choroidal neovascularisation: a retrospective study
por: Bruè, C, et al.
Publicado: (2016)

Fractal analysis of polypoidal choroidal neovascularisation in age-related macular degeneration
por: Serra, Rita, et al.
Publicado: (2021)

Idiopathic Choroidal Neovascularisation as the Inaugural Sign of Multiple Evanescent White Dot Syndrome
por: Papadia, Marina, et al.
Publicado: (2010)

Recurrence risk of myopic choroidal neovascularisation: a systematic review of current study
por: Victor, Andi Arus, et al.
Publicado: (2023)

Webbasierte Genexpressionsanalysen – auf dem Weg zur molekularen Entschlüsselung gesunder und erkrankter Augengewebe
por: Wolf, Julian, et al.
Publicado: (2022)

Web-based gene expression analysis—paving the way to decode healthy and diseased ocular tissue
por: Wolf, Julian, et al.
Publicado: (2022)

Is IL-10 a Good Target to Inhibit Choroidal Neovascularisation in Age-Related Macular Disease?
por: Lightman, Sue, et al.
Publicado: (2006)

Alpinumisoflavone ameliorates choroidal neovascularisation and fibrosis in age-related macular degeneration in in vitro and in vivo models
por: Yu, Eunhye, et al.
Publicado: (2022)

Diagnostic accuracy of OCTA and OCT for myopic choroidal neovascularisation: a systematic review and meta-analysis
por: Ho, Sharon, et al.
Publicado: (2022)

A systematic review and meta-analysis comparing intravitreal ranibizumab with bevacizumab for the treatment of myopic choroidal neovascularisation
por: Loutfi, M., et al.
Publicado: (2015)

Gene expression profiling in a mouse model of retinal vein occlusion induced by laser treatment reveals a predominant inflammatory and tissue damage response
por: Martin, Gottfried, et al.
Publicado: (2018)

Neovascularisation in tendinopathy: from eradication to stabilisation?
por: Järvinen, Tero AH
Publicado: (2020)

Arteriovenous crossing in retinal vessels of mice, rats, and pigs
por: Martin, Gottfried, et al.
Publicado: (2020)

Hyperglycaemia Exacerbates Choroidal Neovascularisation in Mice via the Oxidative Stress-Induced Activation of STAT3 Signalling in RPE Cells
por: Li, Xia, et al.
Publicado: (2012)

Anti-VEGF therapies in the treatment of choroidal neovascularisation secondary to non-age-related macular degeneration: a systematic review
por: Stuart, Arabella, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8p5dq70tv4pspe3v94mflu0uge