Activin-A impedes the establishment of CD4(+) T cell exhaustion and enhances anti-tumor immunity in the lung

BACKGROUND: Although tumor-infiltrating T cells represent a favorable prognostic marker for cancer patients, the majority of these cells are rendered with an exhausted phenotype. Hence, there is an unmet need to identify factors which can reverse this dysfunctional profile and restore their anti-tum...

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Detalles Bibliográficos
Autores principales: Morianos, Ioannis, Tsitsopoulou, Aikaterini, Potaris, Konstantinos, Valakos, Dimitrios, Fari, Ourania, Vatsellas, Giannis, Bostantzoglou, Clementine, Photiades, Andreas, Gaga, Mina, Xanthou, Georgina, Semitekolou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454162/
https://www.ncbi.nlm.nih.gov/pubmed/34548096
http://dx.doi.org/10.1186/s13046-021-02092-5

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