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UPLC-MS/MS method for simultaneously determining nucleosides and methyl-nucleosides in liver mRNA of Epimedin C-induced liver injury mouse model

BACKGROUND: Epimedin C, one of the main active ingredients of Epimedium, has been reported to have potential hepatotoxicity. However, the mechanism of Epimedin C-induced liver injury has not been studied. mRNA methylation, mainly including N6-methyladenosine and N5-methylcytidine, is implicated in t...

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Detalles Bibliográficos
Autores principales:	Song, Zhizhen, Li, Zeyun, Wen, Xueqian, Liu, Ruijuan, Tian, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454167/ https://www.ncbi.nlm.nih.gov/pubmed/34548079 http://dx.doi.org/10.1186/s13020-021-00501-7

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