KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience

There is a pressing need for understanding of factors that confer resilience to pain. Gain-of-function mutations in sodium channel Nav1.7 produce hyperexcitability of dorsal root ganglion neurons underlying inherited erythromelalgia, a human genetic model of neuropathic pain. While most individuals...

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Detalles Bibliográficos
Autores principales: Yuan, Jun-Hui, Estacion, Mark, Mis, Malgorzata A, Tanaka, Brian S, Schulman, Betsy R, Chen, Lubin, Liu, Shujun, Dib-Hajj, Fadia B, Dib-Hajj, Sulayman D, Waxman, Stephen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454204/
https://www.ncbi.nlm.nih.gov/pubmed/34557669
http://dx.doi.org/10.1093/braincomms/fcab212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454204/
https://www.ncbi.nlm.nih.gov/pubmed/34557669
http://dx.doi.org/10.1093/braincomms/fcab212

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