Structure and function of aerotolerant, multiple-turnover THI4 thiazole synthases

Plant and fungal THI4 thiazole synthases produce the thiamin thiazole moiety in aerobic conditions via a single-turnover suicide reaction that uses an active-site Cys residue as sulfur donor. Multiple-turnover (i.e. catalytic) THI4s lacking an active-site Cys (non-Cys THI4s) that use sulfide as sulf...

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Detalles Bibliográficos
Autores principales: Joshi, Jaya, Li, Qiang, García-García, Jorge D., Leong, Bryan J., Hu, You, Bruner, Steven D., Hanson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454699/
https://www.ncbi.nlm.nih.gov/pubmed/34409984
http://dx.doi.org/10.1042/BCJ20210565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454699/
https://www.ncbi.nlm.nih.gov/pubmed/34409984
http://dx.doi.org/10.1042/BCJ20210565

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