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Phosphatidylserine binding directly regulates TIM-3 function

Co-signaling receptors for the T cell receptor (TCR) are important therapeutic targets, with blockade of co-inhibitory receptors such as PD-1 now central in immuno-oncology. Advancing additional therapeutic immune modulation approaches requires understanding ligand regulation of other co-signaling r...

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Detalles Bibliográficos
Autores principales:	Smith, Courtney M., Li, Alice, Krishnamurthy, Nithya, Lemmon, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454703/ https://www.ncbi.nlm.nih.gov/pubmed/34435619 http://dx.doi.org/10.1042/BCJ20210425

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