Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus

Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a bioterrorist threat agent. Recent U.S. Food and Drug Administration approval of the first smallpox anti-viral (tecovirimat) therapeutic was a su...

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Detalles Bibliográficos
Autores principales: Hutson, Christina L., Kondas, Ashley V., Ritter, Jana M., Reed, Zachary, Ostergaard, Sharon Dietz, Morgan, Clint N., Gallardo-Romero, Nadia, Tansey, Cassandra, Mauldin, Matthew R., Salzer, Johanna S., Hughes, Christine M., Goldsmith, Cynthia S., Carroll, Darin, Olson, Victoria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454956/
https://www.ncbi.nlm.nih.gov/pubmed/34547055
http://dx.doi.org/10.1371/journal.ppat.1009633

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