The viral nucleocapsid protein and the human RNA-binding protein Mex3A promote translation of the Andes orthohantavirus small mRNA

The capped Small segment mRNA (SmRNA) of the Andes orthohantavirus (ANDV) lacks a poly(A) tail. In this study, we characterize the mechanism driving ANDV-SmRNA translation. Results show that the ANDV-nucleocapsid protein (ANDV-N) promotes in vitro translation from capped mRNAs without replacing euka...

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Detalles Bibliográficos
Autores principales: Vera-Otarola, Jorge, Castillo-Vargas, Estefania, Angulo, Jenniffer, Barriga, Francisco M., Batlle, Eduard, Lopez-Lastra, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454973/
https://www.ncbi.nlm.nih.gov/pubmed/34547046
http://dx.doi.org/10.1371/journal.ppat.1009931

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