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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy

Autophagy is a cellular process that degrades cytoplasmic cargo by engulfing it in a double-membrane vesicle, known as the autophagosome, and delivering it to the lysosome. The ATG12–5–16L1 complex is responsible for conjugating members of the ubiquitin-like ATG8 protein family to phosphatidylethano...

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Detalles Bibliográficos
Autores principales: Strong, Lisa M, Chang, Chunmei, Riley, Julia F, Boecker, C Alexander, Flower, Thomas G, Buffalo, Cosmo Z, Ren, Xuefeng, Stavoe, Andrea KH, Holzbaur, Erika LF, Hurley, James H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455133/
https://www.ncbi.nlm.nih.gov/pubmed/34505572
http://dx.doi.org/10.7554/eLife.70372