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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
Autophagy is a cellular process that degrades cytoplasmic cargo by engulfing it in a double-membrane vesicle, known as the autophagosome, and delivering it to the lysosome. The ATG12–5–16L1 complex is responsible for conjugating members of the ubiquitin-like ATG8 protein family to phosphatidylethano...
Autores principales: | Strong, Lisa M, Chang, Chunmei, Riley, Julia F, Boecker, C Alexander, Flower, Thomas G, Buffalo, Cosmo Z, Ren, Xuefeng, Stavoe, Andrea KH, Holzbaur, Erika LF, Hurley, James H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455133/ https://www.ncbi.nlm.nih.gov/pubmed/34505572 http://dx.doi.org/10.7554/eLife.70372 |
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