Cargando…

Study on the Mechanism of Qigu Capsule in Upregulating NF-κB/HIF-1α Pathway to Improve the Quality of Bone Callus in Mice at Different Stages of Osteoporotic Fracture Healing

OBJECTIVE: The present study intends to investigate the effects and underlying molecular mechanism of Qigu Capsule (QG) on fracture healing in mice with osteoporosis. METHODS: Ten-week-old female C57BL/6 mice were ovariectomized and three weeks later were evaluated for successful modeling. Then, all...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Peige, Ding, Jie, Yang, Guangyue, Sun, Wen, Guo, Hailing, Zhao, Yongfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455191/ https://www.ncbi.nlm.nih.gov/pubmed/34557256 http://dx.doi.org/10.1155/2021/9943692

Ejemplares similares

Bone morphogenetic protein 9 stimulates callus formation in osteoporotic rats during fracture healing
por: Wang, Xing, et al.
Publicado: (2017)

Short-wave enhances mesenchymal stem cell recruitment in fracture healing by increasing HIF-1 in callus
por: Ye, Dongmei, et al.
Publicado: (2020)

Numerical Simulation of Callus Healing for Optimization of Fracture Fixation Stiffness
por: Steiner, Malte, et al.
Publicado: (2014)

Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus
por: Haffner‐Luntzer, Melanie, et al.
Publicado: (2016)

Inhibition of Midkine Augments Osteoporotic Fracture Healing
por: Haffner-Luntzer, Melanie, et al.
Publicado: (2016)

Inflammatory response in postmenopausal osteoporotic fracture healing
por: Chow, Simon K-H., et al.
Publicado: (2020)

On Provisional Callus in Fractured Bones
por: Hamilton, Frank H.
Publicado: (1853)

Effect of zoledronic acid on fracture healing in osteoporotic patients with intertrochanteric fractures
por: Hayer, Prabhnoor Singh, et al.
Publicado: (2017)

Efficacy and Safety of Teriparatide in Improving Fracture Healing and Callus Formation: A Systematic Review
por: Puvvada, Chaitanya S, et al.
Publicado: (2023)

NF‐κB and HIF crosstalk in immune responses
por: D'Ignazio, Laura, et al.
Publicado: (2015)

Role of Medicinal Plants and Natural Products on Osteoporotic Fracture Healing
por: Abd Jalil, Mohd Azri, et al.
Publicado: (2012)

Nano-copper-bearing stainless steel promotes fracture healing by accelerating the callus evolution process
por: Wang, Lei, et al.
Publicado: (2017)

Odanacatib increases mineralized callus during fracture healing in a rabbit ulnar osteotomy model
por: Pennypacker, Brenda L., et al.
Publicado: (2015)

Functionalized TiCu/TiCuN coating promotes osteoporotic fracture healing by upregulating the Wnt/β-catenin pathway
por: Tan, Jia, et al.
Publicado: (2022)

Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2017)

Anti-Inflammatory Effects of Weigela subsessilis Callus Extract via Suppression of MAPK and NF-κB Signaling
por: Lim, Hyeon-Ji, et al.
Publicado: (2021)

Influence of Early Bisphosphonate Administration for Fracture Healing in Patients with Osteoporotic Proximal Humerus Fractures
por: Seo, Joong-Bae, et al.
Publicado: (2016)

Teriparatide Improves Fracture Healing and Early Functional Recovery in Treatment of Osteoporotic Intertrochanteric Fractures
por: Huang, Tsan-Wen, et al.
Publicado: (2016)

Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia
por: Wank, Isabel, et al.
Publicado: (2022)

Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice
por: Dar, Hamid Y., et al.
Publicado: (2023)

Bone morphogenetic protein-7 accelerates fracture healing in osteoporotic rats
por: Diwan, Ashish D, et al.
Publicado: (2013)

The compositional and nano-structural basis of fracture healing in healthy and osteoporotic bone
por: Mathavan, Neashan, et al.
Publicado: (2018)

Peptide 11R-VIVIT promotes fracture healing in osteoporotic rats
por: Hou, Changju, et al.
Publicado: (2021)

Sesamin Promotes Osteoporotic Fracture Healing by Activating Chondrogenesis and Angiogenesis Pathways
por: Yang, Zhengmeng, et al.
Publicado: (2022)

Effect of Lactobacillus casei fermented milk on fracture healing in osteoporotic mice
por: Guo, Xing, et al.
Publicado: (2022)

Novel approaches to correlate computerized tomography imaging of bone fracture callus to callus structural mechanics
por: Kadkoy, Yazan, et al.
Publicado: (2023)

Evolutionary Conserved Regulation of HIF-1β by NF-κB
por: van Uden, Patrick, et al.
Publicado: (2011)

Systemic Inhibition of Canonical Notch Signaling Results in Sustained Callus Inflammation and Alters Multiple Phases of Fracture Healing
por: Dishowitz, Michael I., et al.
Publicado: (2013)

Sonographic bridging callus at six weeks following displaced midshaft clavicle fracture can accurately predict healing
por: Nicholson, Jamie A., et al.
Publicado: (2021)

Histological Analysis of Bone Callus in Delayed Union Model Fracture Healing Stimulated with Pulsed Electromagnetic Fields (PEMF)
por: Umiatin, U., et al.
Publicado: (2021)

3D ultrasound reconstruction of sonographic callus: a novel imaging modality for early evaluation of fracture healing
por: Nicholson, Jamie A., et al.
Publicado: (2021)

Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice
por: Liu, Jiatong, et al.
Publicado: (2022)

Effect of Cervus and Cucumis Peptides on Osteoblast Activity and Fracture Healing in Osteoporotic Bone
por: Wang, Ai-Yuan, et al.
Publicado: (2014)

Biomechanical Characteristics of Osteoporotic Fracture Healing in Ovariectomized Rats: A Systematic Review
por: Chen, Lin, et al.
Publicado: (2016)

The effects of pentoxifylline adminstration on fracture healing in a postmenopausal osteoporotic rat model
por: Vashghani Farahani, Mohammad Mahdi, et al.
Publicado: (2017)

Effects of BMP-2 compound with fibrin on osteoporotic vertebral fracture healing in rats
por: Ouyang, Xiao, et al.
Publicado: (2021)

Three-Dimensional Computational Model Simulating the Initial Callus Growth during Fracture Healing in Long Bones: Application to Different Fracture Types
por: Naveiro, José M., et al.
Publicado: (2023)

The Sequential and Systemic Administration of BMP-2 and SDF-1α Nanocapsules for Promoting Osteoporotic Fracture Healing
por: Sun, Xiaolei, et al.
Publicado: (2023)

Effects of Zoledronic Acid Treatment on Fracture Healing, Morbidity and Mortality in Elderly Patients with Osteoporotic Hip Fractures
por: Sargin, Serdar, et al.
Publicado: (2019)

Fibrinolysis as a target to enhance osteoporotic fracture healing by vibration therapy in a metaphyseal fracture model
por: Wong, Ronald Man Yeung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j61u4bq67kuh6ju1h65lmtur41