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Activity-dependent release of phosphorylated human tau from Drosophila neurons in primary culture

Neuronal activity can enhance tau release and thus accelerate tauopathies. This activity-dependent tau release can be used to study the progression of tau pathology in Alzheimer's disease (AD), as hyperphosphorylated tau is implicated in AD pathogenesis and related tauopathies. However, our und...

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Detalles Bibliográficos
Autores principales:	Ismael, Sazan, Sindi, Ghadir, Colvin, Robert A., Lee, Daewoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455371/ https://www.ncbi.nlm.nih.gov/pubmed/34473990 http://dx.doi.org/10.1016/j.jbc.2021.101108

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