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Soft Liver Phantom with a Hollow Biliary System

Hepatobiliary interventions are regarded as difficult minimally-invasive procedures that require experience and skills of physicians. To facilitate the surgical training, we develop a soft, high-fidelity and durable liver phantom with detailed morphology. The phantom is anatomically accurate and fea...

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Autores principales: Tan, Xiangzhou, Li, Dandan, Jeong, Moonkwang, Yu, Tingting, Ma, Zhichao, Afat, Saif, Grund, Karl-Enrst, Qiu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455397/
https://www.ncbi.nlm.nih.gov/pubmed/33594636
http://dx.doi.org/10.1007/s10439-021-02726-x
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author Tan, Xiangzhou
Li, Dandan
Jeong, Moonkwang
Yu, Tingting
Ma, Zhichao
Afat, Saif
Grund, Karl-Enrst
Qiu, Tian
author_facet Tan, Xiangzhou
Li, Dandan
Jeong, Moonkwang
Yu, Tingting
Ma, Zhichao
Afat, Saif
Grund, Karl-Enrst
Qiu, Tian
author_sort Tan, Xiangzhou
collection PubMed
description Hepatobiliary interventions are regarded as difficult minimally-invasive procedures that require experience and skills of physicians. To facilitate the surgical training, we develop a soft, high-fidelity and durable liver phantom with detailed morphology. The phantom is anatomically accurate and feasible for the multi-modality medical imaging, including computer tomography (CT), ultrasound, and endoscopy. The CT results show that the phantom resembles the detailed anatomy of real livers including the biliary ducts, with a spatial root mean square error (RMSE) of 1.7 ± 0.7 mm and 0.9 ± 0.2 mm for the biliary duct and the liver outer shape, respectively. The sonographic signals and the endoscopic appearance highly mimic those of the real organ. An electric sensing system was developed for the real-time quantitative tracking of the transhepatic puncturing needle. The fabrication method herein is accurate and reproducible, and the needle tracking system offers a robust and general approach to evaluate the centesis outcome. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10439-021-02726-x.
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spelling pubmed-84553972021-10-05 Soft Liver Phantom with a Hollow Biliary System Tan, Xiangzhou Li, Dandan Jeong, Moonkwang Yu, Tingting Ma, Zhichao Afat, Saif Grund, Karl-Enrst Qiu, Tian Ann Biomed Eng Original Article Hepatobiliary interventions are regarded as difficult minimally-invasive procedures that require experience and skills of physicians. To facilitate the surgical training, we develop a soft, high-fidelity and durable liver phantom with detailed morphology. The phantom is anatomically accurate and feasible for the multi-modality medical imaging, including computer tomography (CT), ultrasound, and endoscopy. The CT results show that the phantom resembles the detailed anatomy of real livers including the biliary ducts, with a spatial root mean square error (RMSE) of 1.7 ± 0.7 mm and 0.9 ± 0.2 mm for the biliary duct and the liver outer shape, respectively. The sonographic signals and the endoscopic appearance highly mimic those of the real organ. An electric sensing system was developed for the real-time quantitative tracking of the transhepatic puncturing needle. The fabrication method herein is accurate and reproducible, and the needle tracking system offers a robust and general approach to evaluate the centesis outcome. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10439-021-02726-x. Springer International Publishing 2021-02-16 2021 /pmc/articles/PMC8455397/ /pubmed/33594636 http://dx.doi.org/10.1007/s10439-021-02726-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Tan, Xiangzhou
Li, Dandan
Jeong, Moonkwang
Yu, Tingting
Ma, Zhichao
Afat, Saif
Grund, Karl-Enrst
Qiu, Tian
Soft Liver Phantom with a Hollow Biliary System
title Soft Liver Phantom with a Hollow Biliary System
title_full Soft Liver Phantom with a Hollow Biliary System
title_fullStr Soft Liver Phantom with a Hollow Biliary System
title_full_unstemmed Soft Liver Phantom with a Hollow Biliary System
title_short Soft Liver Phantom with a Hollow Biliary System
title_sort soft liver phantom with a hollow biliary system
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455397/
https://www.ncbi.nlm.nih.gov/pubmed/33594636
http://dx.doi.org/10.1007/s10439-021-02726-x
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