Cargando…
Soft Urinary Bladder Phantom for Endoscopic Training
Bladder cancer (BC) is the main disease in the urinary tract with a high recurrence rate and it is diagnosed by cystoscopy (CY). To train the CY procedures, a realistic bladder phantom with correct anatomy and physiological properties is highly required. Here, we report a soft bladder phantom (FlexB...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455490/ https://www.ncbi.nlm.nih.gov/pubmed/34002287 http://dx.doi.org/10.1007/s10439-021-02793-0 |
_version_ | 1784570676206632960 |
---|---|
author | Choi, Eunjin Waldbillig, Frank Jeong, Moonkwang Li, Dandan Goyal, Rahul Weber, Patricia Miernik, Arkadiusz Grüne, Britta Hein, Simon Suarez-Ibarrola, Rodrigo Kriegmair, Maximilian Christian Qiu, Tian |
author_facet | Choi, Eunjin Waldbillig, Frank Jeong, Moonkwang Li, Dandan Goyal, Rahul Weber, Patricia Miernik, Arkadiusz Grüne, Britta Hein, Simon Suarez-Ibarrola, Rodrigo Kriegmair, Maximilian Christian Qiu, Tian |
author_sort | Choi, Eunjin |
collection | PubMed |
description | Bladder cancer (BC) is the main disease in the urinary tract with a high recurrence rate and it is diagnosed by cystoscopy (CY). To train the CY procedures, a realistic bladder phantom with correct anatomy and physiological properties is highly required. Here, we report a soft bladder phantom (FlexBlad) that mimics many important features of a human bladder. Under filling, it shows a large volume expansion of more than 300% with a tunable compliance in the range of 12.2 ± 2.8 – 32.7 ± 5.4 mL cmH(2)O(−1) by engineering the thickness of the bladder wall. By 3D printing and multi-step molding, detailed anatomical structures are represented on the inner bladder wall, including sub-millimeter blood vessels and reconfigurable bladder tumors. Endoscopic inspection and tumor biopsy were successfully performed. A multi-center study was carried out, where two groups of urologists with different experience levels executed consecutive CYs in the phantom and filled in questionnaires. The learning curves reveal that the FlexBlad has a positive effect in the endourological training across different skill levels. The statistical results validate the usability of the phantom as a valuable educational tool, and the dynamic feature expands its use as a versatile endoscopic training platform. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10439-021-02793-0) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-8455490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-84554902021-10-07 Soft Urinary Bladder Phantom for Endoscopic Training Choi, Eunjin Waldbillig, Frank Jeong, Moonkwang Li, Dandan Goyal, Rahul Weber, Patricia Miernik, Arkadiusz Grüne, Britta Hein, Simon Suarez-Ibarrola, Rodrigo Kriegmair, Maximilian Christian Qiu, Tian Ann Biomed Eng Original Article Bladder cancer (BC) is the main disease in the urinary tract with a high recurrence rate and it is diagnosed by cystoscopy (CY). To train the CY procedures, a realistic bladder phantom with correct anatomy and physiological properties is highly required. Here, we report a soft bladder phantom (FlexBlad) that mimics many important features of a human bladder. Under filling, it shows a large volume expansion of more than 300% with a tunable compliance in the range of 12.2 ± 2.8 – 32.7 ± 5.4 mL cmH(2)O(−1) by engineering the thickness of the bladder wall. By 3D printing and multi-step molding, detailed anatomical structures are represented on the inner bladder wall, including sub-millimeter blood vessels and reconfigurable bladder tumors. Endoscopic inspection and tumor biopsy were successfully performed. A multi-center study was carried out, where two groups of urologists with different experience levels executed consecutive CYs in the phantom and filled in questionnaires. The learning curves reveal that the FlexBlad has a positive effect in the endourological training across different skill levels. The statistical results validate the usability of the phantom as a valuable educational tool, and the dynamic feature expands its use as a versatile endoscopic training platform. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10439-021-02793-0) contains supplementary material, which is available to authorized users. Springer International Publishing 2021-05-17 2021 /pmc/articles/PMC8455490/ /pubmed/34002287 http://dx.doi.org/10.1007/s10439-021-02793-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Choi, Eunjin Waldbillig, Frank Jeong, Moonkwang Li, Dandan Goyal, Rahul Weber, Patricia Miernik, Arkadiusz Grüne, Britta Hein, Simon Suarez-Ibarrola, Rodrigo Kriegmair, Maximilian Christian Qiu, Tian Soft Urinary Bladder Phantom for Endoscopic Training |
title | Soft Urinary Bladder Phantom for Endoscopic Training |
title_full | Soft Urinary Bladder Phantom for Endoscopic Training |
title_fullStr | Soft Urinary Bladder Phantom for Endoscopic Training |
title_full_unstemmed | Soft Urinary Bladder Phantom for Endoscopic Training |
title_short | Soft Urinary Bladder Phantom for Endoscopic Training |
title_sort | soft urinary bladder phantom for endoscopic training |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455490/ https://www.ncbi.nlm.nih.gov/pubmed/34002287 http://dx.doi.org/10.1007/s10439-021-02793-0 |
work_keys_str_mv | AT choieunjin softurinarybladderphantomforendoscopictraining AT waldbilligfrank softurinarybladderphantomforendoscopictraining AT jeongmoonkwang softurinarybladderphantomforendoscopictraining AT lidandan softurinarybladderphantomforendoscopictraining AT goyalrahul softurinarybladderphantomforendoscopictraining AT weberpatricia softurinarybladderphantomforendoscopictraining AT miernikarkadiusz softurinarybladderphantomforendoscopictraining AT grunebritta softurinarybladderphantomforendoscopictraining AT heinsimon softurinarybladderphantomforendoscopictraining AT suarezibarrolarodrigo softurinarybladderphantomforendoscopictraining AT kriegmairmaximilianchristian softurinarybladderphantomforendoscopictraining AT qiutian softurinarybladderphantomforendoscopictraining |