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Estimated Prevalence and Number of PiMZ Genotypes of Alpha-1 Antitrypsin in Seventy-Four Countries Worldwide

BACKGROUND: The α-1 antitrypsin (AAT) protease inhibitor PiMZ is a moderately deficient genotype, until recently considered of little or negligible risk. However, a growing number of studies show that MZ carriers have an increased risk of developing lung and liver diseases, if exposed to smoking or...

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Detalles Bibliográficos
Autores principales: Martinez-González, Cristina, Blanco, Ignacio, Diego, Isidro, Bueno, Patricia, Miravitlles, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455519/
https://www.ncbi.nlm.nih.gov/pubmed/34556982
http://dx.doi.org/10.2147/COPD.S327803