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Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism

Metformin is a first-line drug in the treatment of type-2 diabetes mellitus (T2DM). In addition to its antigluconeogenic and insulin-sensitizing properties, metformin has emerged as a potent inhibitor of the chronic inflammatory response of macrophages. In particular, metformin treatment has been sh...

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Detalles Bibliográficos
Autores principales:	Postler, Thomas S., Peng, Vincent, Bhatt, Dev M., Ghosh, Sankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455559/ https://www.ncbi.nlm.nih.gov/pubmed/34548527 http://dx.doi.org/10.1038/s41598-021-97441-x

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