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Chronic exposure to tramadol induces cardiac inflammation and endothelial dysfunction in mice
Tramadol is an opioid extensively used to treat moderate to severe pain; however, prolonged therapy is associated with several tissues damage. Chronic use of tramadol was linked to increased hospitalizations due to cardiovascular complications. Limited literature has described the effects of tramado...
Autores principales: | Bakr, Marwa H., Radwan, Eman, Shaltout, Asmaa S., Farrag, Alshaimaa A., Mahmoud, Amany Refaat, Abd-Elhamid, Tarek Hamdy, Ali, Maha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455605/ https://www.ncbi.nlm.nih.gov/pubmed/34548593 http://dx.doi.org/10.1038/s41598-021-98206-2 |
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