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Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures
We are now in an era of molecular medicine, where specific DNA alterations can be used to identify patients who will respond to specific drugs. However, there are only a handful of clinically used predictive biomarkers in oncology. Herein, we describe an approach utilizing in vitro DNA and RNA seque...
Autores principales: | Rydzewski, Nicholas R., Peterson, Erik, Lang, Joshua M., Yu, Menggang, Laura Chang, S., Sjöström, Martin, Bakhtiar, Hamza, Song, Gefei, Helzer, Kyle T., Bootsma, Matthew L., Chen, William S., Shrestha, Raunak M., Zhang, Meng, Quigley, David A., Aggarwal, Rahul, Small, Eric J., Wahl, Daniel R., Feng, Felix Y., Zhao, Shuang G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455625/ https://www.ncbi.nlm.nih.gov/pubmed/34548481 http://dx.doi.org/10.1038/s41525-021-00239-z |
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